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Human Genome

3 billion base pairs — the complete blueprint of a human being.

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The Human Genome Project (1990–2003), involving 20 institutions across 6 countries, sequenced the complete human genome — all 3 billion base pairs (letters of DNA) encoding approximately 20,000–25,000 genes. Celebrated as biology's 'Moon shot,' it cost $2.7 billion. Today, a human genome can be sequenced for under $1,000 in about 24 hours. The genome sequence has enabled precision medicine (treatments tailored to genetic profiles), cancer genomics (identifying cancer's genetic drivers), ancestry testing (23andMe, AncestryDNA), and CRISPR gene therapy. Surprising discoveries include that 98–99% of human DNA doesn't code for proteins (once dismissed as 'junk DNA' but now known to have regulatory functions) and that modern humans contain 1–4% Neanderthal DNA.

# Top 10 Human Genome facts

  1. 1The Human Genome Project cost $2.7 billion — today a genome can be sequenced for under $1,000
  2. 2Modern humans carry 1–4% Neanderthal DNA — evidence of ancient interbreeding
  3. 398–99% of human DNA doesn't code for proteins — once called 'junk DNA,' now known to regulate gene expression

Fascinating Facts

  • The Human Genome Project cost $2.7 billion — today a genome can be sequenced for under $1,000
  • Modern humans carry 1–4% Neanderthal DNA — evidence of ancient interbreeding
  • 98–99% of human DNA doesn't code for proteins — once called 'junk DNA,' now known to regulate gene expression
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